Think about the question how new genes are created, and how genome size can increase. Everyone should have at least three distinct mechanisms.
Discussion of gene plot via blast (slides with examples)
Discuss gene and genome rearrangements.
- How would a misplaced origin of replication look like in two similar genomes?
- Which part of a circular bacterial genome is least conserved?
- Aside strand bias: (G/G+C) other biases.
Discussion of selected questions from midterm.